This FEBS Combined Practical & Lecture Course is intended to bring together computational and experimental enzymologists who will give comprehensive lectures towards understanding and engineering enzyme catalysis. Hands-on practical sessions will be focused on how to use state-of-the-art software and web servers to understand carefully chosen phenomena in this research field. Experimental researchers will give lectures on how these in silico approaches have successfully helped them with solving problems in their research related to understanding and engineering enzyme catalysis

Organizers: Aleksandra Maršavelski, Tomica Hrenar, Jiří Damborský, Outi Lampela, Tiila-Riikka Kiema, Rikkert Wierenga

This Joint FEBS/EMBO Lecture Course will provide PhD students and postdocs with a detailed overview of the different aspects of cellular protein homeostasis (proteostasis) – from protein biogenesis to folding, trafficking and degradation – and its role in disease. The interactive program aims to foster interactions between scientific generations to discuss science, gain critical feedback on individual projects and career paths, and build connections.

Organizers: Christian Münch

The last few years have reinforced the concept that sphingolipids are relevant for human health and defects in their metabolism contribute to the aetiology of diverse diseases. Despite an extensive effort to understand what biology is dependent on a well-balanced sphingolipid metabolic pathway, we are still lacking a unifying picture of sphingolipid role in physiology. This FEBS Special Meeting –  SLBiol2023 – proposes to summon the sphingolipid community to discuss about the basic principles of sphingolipid biology and about how they can be integrated to explain the role of sphingolipids in human health.

Organizers: Liana C. Silva, Giovanni D’Angelo, Fikadu Tafesse

This 5-day Advanced Lecture Course will cover a wide range of topics in cellular stress and ADP-ribosylation, from basic concepts, to recent breakthroughs, advanced techniques, and clinical implication. Session topics include systems-wide ADP-ribosylation, NAD biosynthesis and signaling, protein homeostasis and proteostasis, heat-shock, genotoxic stress responses, mitochondrial dysfunction and ADP-ribosylation from virus to cancer. The program provides participants with ample opportunities for presenting and discussing their own work (poster sessions, selected short talks or meet the speakers/experts session).

Picture: MCF7 cells treated with IL8; green: actin; red: SHP1 phosphatase (a protein involved in the regulation of cancer invasion). By Alessia Varone.

Organizers: Daniela Corda, Giovanna Grimaldi, Michael O. Hottiger ([email protected])