HFP2024: Molecular mechanisms of host–pathogen interactions and virulence in human fungal pathogens
The primary objective of this course is to share the latest knowledge regarding the biochemical, molecular, and genetic mechanisms of fungal pathogenesis with early-career scientists. Additionally, it aims to create valuable networking opportunities for them with renowned experts in this dynamic research field. Through these efforts, the course will play a significant role in enhancing the training of PhD students and post-doctoral fellows engaged in the investigation of fungal pathogens and the control of fungal infections.(Photo credit: Vishu Kumar Aimanianda.)
Website under preparation.
Organizers: Guilhem Janbon, Mike Lorentz, Elaine Bignell
19–23 May 2024
Transglutaminases in human disease processes
The transglutaminase enzymes are extremely important to normal biological function, having been recognized to perform a myriad of roles relating to signal transduction and protein crosslinking. Dysregulation of their function or expression is the basis of a host of pathologic conditions including fibrosis, inflammation, cancer, celiac disease, skin diseases, diabetes, blood disorders and neurodegenerative disease, and there is a tremendous interest in transglutaminase type 2 as a therapeutic target.
The proposed FEBS Workshop is a much anticipated scientific meeting on known and emerging transglutaminase-related diseases, new methods for detection and novel translational aspects for treatment. It aims to bring together an international group of senior academic and industrial members, with as many as possible early career scientists, future leaders and drivers of this expanding field. The Workshop will feature presentations relevant to all the pathological conditions for which transglutaminase is a relevant target, and will also focus on emerging diseases associated with this class of enzymes, and new methods for their investigation. Additional training sessions will focus on career development and grant capturing. There will be plenty of opportunities for poster or selected oral presentations. Our evening programme is designed to encourage networking and to enjoy all that idyllic Bertinoro has to offer.
The ability of cells to perceive and correctly respond to their environment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in the interplay, dynamics or localization of the involved molecules are responsible for many diseases such as cancer, autoimmunity and diabetes. By increasing the understanding of the complex interplay between these various components and their dynamics over time the related diseases can be treated more effectively. Because of the recent technological revolution in advanced light microscopy (i.e. functional imaging of molecules, development of caged compounds and biosensors) it is now possible to directly monitor the dynamics of (single) molecules in living cells. Several new microscopy techniques are ideally suited for studying cellular signals but their application remains limited because most biologists have never been introduced to these technologies.
This 6-day FEBS Practical Course on advanced microscopy for experienced graduate students, postdocs and lab technicians integrates theoretical lectures with hands-on experiments and practical experience. National and international experts in the field of microscopy will give an overview of “state-of-the-art” imaging techniques and applications in biological research. The practicals will focus at the functional imaging techniques FRAP, FCS, FLIM, FRET & Optogenetics. In addition two (advanced) data analysis sessions for ImageJ will be included.
Website under preparation.
Organizers: Mark Hink
9–15 June 2024
Ceske Budejovice, Czech Republic
Advanced methods in macromolecular crystallization X
Twenty years ago, the initial FEBS crystallization course took place in the Czech Republic, becoming a celebrated tradition for students and postdocs worldwide. Not even pandemics halted its continuity, with the ninth course held offline in August 2021. Given its enduring popularity, the organizers will organize the tenth-anniversary edition in June 2024. While cryoEM advances have transformed structural biology, X-ray diffraction remains vital, particularly for studying protein–inhibitor/substrate complexes. However, the challenges in biological macromolecule crystallization persist. The course aims to bridge the gap between new insights and practical application, fostering rational approaches. Renowned experts will guide students, maintaining the tradition of these successful courses, with added topics such as fragment-screening, intracellular crystallization, and cryo-EM basics. The course’s practical focus, theory discussions, and laboratory experiments create a unique learning experience, building on past successes. Lecturers from the past courses are invited, providing their valuable expertise to participants.
The Essential Molecular Biology course covers the fundamental principles and techniques used in experimental research in the area of Molecular Biology. Essentially practical in nature, it aims at the learning of current genomics and proteomics techniques, as well as the acquisition of skills in laboratory experimentation required for scientific research in Biomedicine. An exciting way to learn the essential genomics and proteomics techniques used in experimental research in biomedicine: hands-on, practical, intensive.
1st call – Applications: 26 Feb – 18 Mar / Registration: 12 – 26 Apr 2024
2nd call – Applications: 2 – 13 May / Registration: 6 – 13 Jun 2024
Foreign participants needing a VISA to travel to Portugal to attend the course should apply in the 1st call.
Organizers: Faculty of Medicine of the University of Porto
24–28 June 2024
Cell biology of host-pathogen interactions
Microbial infections lead to drastic changes in the architecture and metabolism of the host cell. The inaugural FEBS/EMBO Lecture Course on Cell Biology of Host-Pathogen Interactions explores the mechanisms underlying these changes, and the functions they serve during infection from both the host and pathogen perspective. Themes highlighted include: metabolic control of and manipulation by pathogens, organelle-microbe conflict, the regulation of intracellular compartments, formation of distinct pathogen vacuoles, avoidance of cell-autonomous innate immunity, and emerging technologies that can be applied to the host-pathogen interaction. (Photo credit: Lena Pernas.)
Website under preparation. Sign up here to to be alerted to the website.
The FEBS Young Scientists’ Forum (YSF) is a popular event for about 100 PhD students and postdocs mostly from the FEBS area that takes place in conjunction with – and just before – the annual FEBS Congress. Selected applicants are supported by FEBS grants. The YSF comprises opportunities for participants to present their own research work, receive career advice, hear and meet keynote lecturers, and enjoy a social programme. YSF participants also go on to experience the FEBS Congress, which is one of the largest gatherings in the biosciences in Europe.
Deadline for applications: 7 December 2023
29 June – 3 July 2024
48th FEBS Congress – ‘Mining biochemistry for human health and well-being’
‘FEBS 2024’ will include several plenary lectures from outstanding research leaders, for inspiration and a broad perspective on recent research progress across the molecular and cellular life sciences; symposia sessions offering deeper dives into important research areas; special sessions for additional interest; and opportunities for those attending to be active participants by presenting their own work as talks or posters. See you in Milano!