The FEBS Open Bio Article Prize 2021
The FEBS Open Bio Article Prize is awarded to an early career researcher (a PhD student or a postdoctoral researcher within 5 years of receiving their PhD) who has published a paper of especial interest and importance in the journal in the preceding year. The prize consists of a bursary for registration, travel and accommodation to allow the winner to attend the FEBS Congress. We are pleased to announce that the inaugural 2021 FEBS Open Bio Article Prize will be awarded to Dr Arpit Katiyar (formerly of Yamaguchi University School of Medicine, Ube, Japan).
HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response
Arpit Katiyar, Mitsuaki Fujimoto, Ke Tan, Ai Kurashima, Pratibha Srivastava, Mariko Okada, Ryosuke Takii and Akira Nakai. FEBS Open Bio, 2020, 10(6):1135–1148. doi: 10.1002/2211-5463.12863
The mitochondrial unfolded protein response (UPRmt) is characterized by the transcriptional induction of mitochondrial chaperone and protease genes in response to impaired mitochondrial proteostasis. In this article, the authors showed that the heat shock transcription factor HSF1 is required for activation of mitochondrial chaperone genes in mouse embryonic fibroblasts during impaired mitochondrial proteostasis. The authors also observed that HSF1 binds constitutively to mitochondrial chaperone gene promoters and it supports the maintenance of mitochondrial function. The findings in this award-winning paper suggest that HSF1 is required for induction of mitochondrial chaperones during the UPRmt.
The winning article was selected during a meeting hosted by the journal’s editorial manager Duncan Wright by a jury comprised of three members of the journal’s Editorial Board: Stuart Ferguson (Oxford), Takashi Gojobori (Mishima), and Alex Wlodawer (Frederick).
Dr Katiyar has been invited to submit an abstract on his current work for presentation at the 46th FEBS Congress to be held in Lisbon, Portugal, 9–14 July 2022.
For more information about this award, please see the FEBS Open Bio Article Prize.
For a summary of all FEBS awards, click here.