Postdoc position in feeding behavior, Umeå University, Sweden
The laboratory of Olof Lagerlöf at Umeå University in Sweden is seeking one or two postdoctoral fellows to study the neurobiology of feeding behavior.
As postdoctoral fellow you will lead a project asking how specific neuronal circuits regulate food intake. The project involves neuronal circuit mapping and behavioral analyses in rodents. It is also possible to focus on molecular mechanisms by which neurons in the brain communicate to influence what, when and how much we eat. For motivated candidates we are able to set up a project investigating neuronal circuitry underlying eating disorders, particularly anorexia nervosa.
Contact: Olof Lagerlöf at [email protected]
Start date: January 2022 or by agreement.
Application deadline: 17 November 2021
Postdoctoral positions in physico-chemical biology, Institut de Biologie Physico-Chimique, Collège de France, Ecole Normale Supérieure in Paris, France
The COFUND FP-DYNAMO-PARIS programme offers 13 post-doctoral positions in the field of physico-chemical biology. The goal of the research programme is to integrate knowledge on gene expression, structural and membrane biology, and bioenergetics in bacteria, chloroplasts and mitochondria in the general context of improving our understanding the biogenesis of energy-transducing membranes. These studies will involve cutting-edge technologies including structural biology (NMR, X-ray crystallography and CryoEM), RNA sequencing, mass-spectrometry, synthetic biology, microfluidics, computational modelling and visualization.
Post-doctoral fellows will have the opportunity of developing their research projects in a dynamic scientific environment covering three main research themes I) RNA biology from bacteria to chloroplasts, II) membrane system dynamics and II) computational modelling of molecular assemblies.
We offer two-year post-doc positions (one year with renewal of one year) for 9 of the projects; 4 projects are funded for one year only. Other benefits include competitive salary, work in a dynamic team of researchers with backgrounds in different disciplines across biology, chemistry, physics and computational science; convivial, international environment in a human-sized atmosphere on the Montagne St-Geneviève campus, in the Latin quarter of Paris; mentoring programmes to support career development.
Projects starting: January 1, 2022
Application deadline: 17 November 2021
Postdoc position on neurodegeneration-linked RNA-binding proteins, Institute of Molecular Biology in Mainz, Germany
The laboratory of Dorothee Dormann at Mainz University and the Institute of Molecular Biology (IMB) is looking for a Postdoctoral Researcher to work on post-translational modifications on neurodegeneration-linked RNA-binding proteins. Our postdocs benefit from the training activities and active support for their career development through our IMB Postdoc Programme (IPPro).
The successful candidate will systematically identify PTMs on TDP-43 and FUS in neuron-like cells exposed to different stress conditions and in ALS/FTD post-mortem brains. The functional impact of diverse PTMs on the proteins’ biophysical properties and phase separation/aggregation behaviour, on their interactions with nucleic acids and RNA regulatory functions, and their subcellular localization and transport will be addressed.
The candidate will have the chance to develop and apply a variety of biophysical, biochemical and cellular techniques to study the functions of post-translational modifications on disease linked RNA-binding proteins. For more information on the project and requirements, please visit its webpage.
We are looking for highly curious and open-minded applicants, motivated to develop and drive an ambitious project. Applicants should hold a PhD (or be about to complete their doctoral studies) in biochemistry, biology, biophysics or related disciplines. Applicants will have extensive experience with mass spectrometry or biophysical characterization of IDPs. We seek team players with enthusiasm to engage in collaborations and other lab projects.
Postdoc position in specificity in selective protein degradation, Institute of Molecular Biology in Mainz, Germany
The research group of Anton Khmelinskii at the Institute of Molecular Biology (IMB) focuses on how protein quality systems change in healthy, diseased or aged cells. We are looking for an outstanding Postdoctoral Researcher to address how cells deal with different types of abnormal proteins.
The successful candidate will join an international team and develop an interdisciplinary project, combining deep mutational scanning, phage display, biochemical and computational analyses to systematically dissect specificity determinants in the UPS. With strong support for genomics and proteomics from IMB Core Facilities, the project aims at systematically identifying degradation signals (degrons) recognized by different UPS components and uncovering functions of such degron motifs in disease.
We are looking for applicants with extensive experience with budding yeast and high-throughput yeast genetics, and experience with genetic screens and deep mutational scanning. Candidates should hold (or be about to complete) a PhD in molecular or cell biology, genetics, systems biology or related disciplines. Applicants will have excellent organizational skills, the ability to work independently, work experience in interdisciplinary teams and excellent communication skills in English.
Candidates are requested to submit a 1-page cover letter explaining the reasons to join our group, a concise project proposal, curriculum vitae and 2 references. For more information on the project, please visit its webpage.
Postdoctoral positions to study DNA/RNA epigenetic modifications, Institute of Molecular Biology in Mainz, Germany
The Niehrs laboratory at the Institute of Molecular Biology (IMB) studies regulatory DNA and RNA modifications in development & disease. We are looking for two Molecular Biologists to join our ERC-funded group. Postdoctoral Researcher benefit from training activities and active support for their career development through our IMB Postdoc Programme (IPPro).
Project 1: non-coding RNA & R-loop epigenetics
In an ERC-funded project, the role of ncRNAs and R-loops in targeting GADD45a and the DNA demethylation machinery in the genome will be investigated, based on mouse embryonic stem cells (ESCs), CRISPR/CAS9-mediated ESC mutants, as well as ChIP-seq, RNA-seq and bisulfite-seq. The project will involve strong interaction between Molecular- and Computational Biologists.
Nucleic acid modifying enzymes will be studied to find out how chemical changes in DNA, RNA and R-loops regulate pluripotency and differentiation of embryonic stem cells and mammalian embryos. We will use mass spectrometry, genome-edited CRISPR/Cas9 stem cell mutants and various NGS protocols to perform a multidimensional analysis.
Applicants should currently hold a PhD (or be about to complete their doctoral studies), will have publications in a relevant field and sound experience in molecular biology. Fluency in English is required, as this is the working language at IMB.
Doctoral positions in microbiology, genetics and plant science at the Graduate School Life Science, Ludwig Maximilian University of Munich, Germany
The Graduate School Life Science Munich (LSM) offers an international doctoral programme to motivated and academically qualified next generation researchers at one of Europe’s top Universities. LSM members are internationally recognized for their innovative research approaches and technologies, they are aiming to answer essential questions relevant to basic and applied biological and biochemical research. Within their own research group or in collaboration with a specialized research group on campus, LSM doctorates are given the opportunity to learn and command a variety of techniques. Furthermore, the graduate programme holds various workshops and seminars that strengthen and prepare doctorates for a successful career as scientists.
LSM calls for doctoral applications on a yearly basis, open from the 1st of October until the 30th of November 2021. Available research projects cover areas from Cell and Developmental Biology, Epigenetics, Genetics, Microbiology, Molecular Biology, Biochemistry, Evolutionary Biology, Plant Sciences, Pharmacology, and Systematics.
Further information and details about the online application process and the available funded research projects can be found here: https://www.lsm.bio.lmu.de/apply/index.html
Additionally, the DAAD and LSM jointly award 2 full scholarships for doctoral study financed by the DAAD Graduate School Scholarship Programme (GSSP). Further information and details about the online application process and the available DAAD scholarships can be found here: https://www.lsm.bio.lmu.de/daad-lsm-application/index.html
Apply now through the online application portal here https://www.portal.graduatecenter.uni-muenchen.de/ocgc/lsm
Deadline: 30 November 2021
Starting Date: Summer/Autumn 2022
Postdoctoral researcher position in molecular and synthetic microbiology, Ludwig Maximilian University of Munich, Germany
The LMU working group “Microbial Biochemistry” invites applications for the position of a Postdoctoral Researcher (m/f/d) in the Field of Molecular and Synthetic Microbiology (Salary Scale E13 TV-L, 100%) starting in January 2022. The position is initially limited to one year and funded by the Boehringer Ingelheim foundation.
The selected candidate will contribute to the group’s work on translational regulation. The candidate is expected to work on genetic code expansion and evolution of a novel type of bacterial tRNAsynthetase. By using microbial genetics and biochemistry the group aims to evolve new substrate specificities in order to develop a molecular tool to generate artificial proteins with new functionalities. The position offers the opportunity to develop a scientific profile and is thus intended as a starting point for an independent scientific career.
You must have a university PhD degree in microbiology, biochemistry, genetics, molecular biology or a related subject as well as experience in working with bacteria. Extensive knowledge with molecular biological and biochemical methods is strongly recommended. Evidence of successful scientific activity through publications is desirable.
For further information and to apply:
Contact: [email protected]
Start date: 22 January 2022
Application deadline: We will constantly evaluate incoming applications until the position is filled.
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