Postdoctoral position in Neurobiology at KU Leuven, Belgium
The adult mammalian brain possesses two neurogenic niches of which the neurogenic potential declines steeply with age. Yet teleost fish possess 16 niches and exhibit a very high potential for adult neurogenesis. They can regenerate tissue, including brain, upon injury. The African turquoise killifish recently gained much attention as potent ageing model based on its short life cycle, explosive growth and the finding of peculiar and abundant highly-proliferative neuronal progenitor cells (hpNPCs) in its telencephalon, next to the commonly recognized radial glia type NPCs as in zebrafish. The exact molecular nature of these hpNPCs and possibly other killifish NPC types remains elusive. Their involvement in neuro-re-generation in the (injured) (aged) brain is the topic of this project, targeted at finding new therapies to adapt the non-permissive environment of the aged mammalian brain to combat neurodegenerative disease.
We will characterize in-depth the different stem cell populations at transcriptome and proteome level in the killifish telencephalon, and define their phenotype in neurogenesis in the young and aged brain. We aim at restoring the decline in neurogenesis via reactivation of NPC-specific genes/proteins and pathways identified in the differential genetic/proteomic screen.
Your profile: a PhD in Sciences; knowledge in stem cell biology and regeneration is mandatory, track record in bioinformatics is desirable; experience with killifish - zebrafish neurobiology is a plus; at least 1 paper in a major international journal as 1st author.
Offer: 3-year full-time position (1 year initial contract, + 2 years upon positive evaluation)
Please apply to email@example.com with a cover letter describing previous experience, career goals, your motivation, contact information of 2-3 references, your detailed CV. Closing date: 28 March 2018
Find out more via https://bio.kuleuven.be/df/la
PhD positions, Medical University of Graz, Austria
PhD positions in the PhD Programs DP-iDP, MolMed and AMBRA | Projects starting October 1, 2018 | Application deadline: April 2, 2018
The Medical University of Graz and the Austrian Science Fund (FWF) offer PhD positions in the international PhD programs in “Inflammatory Disorders in Pregnancy” (DP-iDP), “Molecular Medicine” (MolMed) and “Advanced Medical Biomarker Research” (AMBRA). The PhD studies provide an in-depth, multidisciplinary training in biomedical research in a stimulating international environment. The thesis projects focus on aspects of inflammatory diseases with a special focus in pregnancy, metabolic and cardiovascular diseases, cancer, as well as novel therapeutic targets and the development of medical biomarkers and therapies, and integrate basic research and clinically-oriented sciences utilizing a wide spectrum of state-of-the-art techniques.
Selected PhD students get employed for up to 3 years (initial contract for one year with the option of prolongation upon successful performance) with a contract that includes social benefits. Moreover, DP-iDP students will be encouraged to spend up to one year abroad joining other collaborating laboratories with the possibility of a 4th year extension of their contract.
Applicants must hold (or be close to obtaining) an undergraduate degree equivalent to a Master in any discipline of natural or life sciences or medicine. The selection procedure, all training activities and communications will be in English. Thus, excellent written and spoken English skills are required.
Applications are exclusively accepted through the online platform https://mug.glowbase.com/. Please do not send any documents by regular mail or e-mail unless you are explicitly asked to do so by our staff. There is no application fee.
Further information about the programs, open projects and the online application procedure are available at: http://www.medunigraz.at/phd/application/
PhD student position, Masaryk University Brno, Czech Republic
We are seeking a talented and motivated candidate to join a research team headed by Dr. Lukáš Čajánek at Masaryk University (Faculty of Medicine, Department of Histology and Embryology), in Brno, Czech Republic. The selected candidate will have an opportunity to work on following projects:
- Impact of centrosome abnormalities on human embryonic stem cells and their differentiated progeny
- Molecular mechanisms controlling formation of primary cilia in human cells
The position is supported by funding from Czech Science Foundation (GACR), and Swiss National Science Foundation (SNSF). More information about the research team and host institution can be found here:http://www.cajaneklab.com/ and http://www.med.muni.cz/histology/
We expect the selected candidate to:
• Be interested and motivated to tackle scientific problems, formulate hypothesis and ways how to address them
• Be smart, self-driven, collaborative and eager to learn
• Have a background in molecular and/or cell biologyApplication deadline: 30 June 2018
Expected start: September 2018 or upon agreement
How to apply: send you CV + motivation letter or informal inquiry to Dr. Lukas Cajanek at firstname.lastname@example.org
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